LucKI Gut Study
Networks
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Datasets
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Variables
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Infant microbiome development in association to allergies and weight development
- Start Year
- 2017
- Funding
- JPI HDHL Intestinal Microbiomics
Visit LucKI Gut Study
| Investigators | Contacts |
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Design
- Study design
- Cohort
- Follow Up
- yes, ongoing, 1.5 years, completed
Recruitment
- Sources of Recruitment
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- Individuals
Number of participants
- Number of participants
- 149
- Number of participants with biosamples
- Supplementary Information
- 83 M 61 F
Timeline
lucki-gut-study
Selection Criteria
- Minimum age
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0
- Newborns
- Twins
- Countries
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- Netherlands
- International/National/Regional (region name)
- Regional (South Limburg, Netherlands)
- Ethnic Origin
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- Health Status
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- Other criteria
- Aterm birth (>= 37 weeks)
Recruitment
- Sources of recruitment
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- Other : Population-based - expecting parents in Province South Limburg
Number of participants
- Number of participants
- 149
- Number of participants with biosamples
- 149
Data Collection Event
- Start Date
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2017
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Measurements & methods
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Dietary intake
- yes/no
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- Information collected on habitual food intake collected
- Information collected on type of diet (vegetarian/vegan/omnivore)
- Special dietary aspects collected (e.g. supplements, probiotics, prebiotics and synbiotics)
- Methods
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- FFQ
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FFQ
- Questionnaire name/set of questions
- Set of questions on infant feeding (milk and solids) / set of questions on maternal diet
- Type of questionnaire
- Semi-quantitative
- Administration method
- Self-reported
- Administration type
- Web/computer-based
- Number of food items
- Age-dependent (35 items at age 9 months)
- Reference period
- Age-dependent, (for age 11m and 14m: 1 month)
- Frequency categories
- Infants:continous / mothers: 6 categories
- Portion size estimation
- Standard portion sizes without aids
- Reproducibility
- Newly developed
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Alcohol consumption
- Information collected
- Timing of alcohol consumption (1st, 2nd, 3rd trimester of pregnancy or after birth of child)
- Questionnaire name/set of questions
- 1 question
- Administration method
- Self-reported
- Administration type
- Paper-based
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Tobacco consumption
- Information collected
- Maternal smoking before, during and after index pregnancy (timing, frequency), paternal smoking (frequency), ETS
- Questionnaire name/set of questions
- Set of questions
- Administration method
- Self-reported
- Administration type
- Web/computer-based
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Physical activity
- Information collected
- Type and duration
- Questionnaire name/set of questions
- Set of questions
- Administration method
- Self-reported
- Domains covered
- Leisure
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Anthropometric measurements
- Weight/height
- Measured
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Sociodemographic information
- Information collected
- Sex, age, residence/country of birth
- Questionnaire name/set of questions
- Set of questions
- Administration method
- Self-reported
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Medication
- Information collected
- Not yet collected to date, but informed consent available to extract this information from registry
- Questionnaire name/set of questions
- Set of questions
- Antibiotics
- Last treatment and frequency collected
- Administration method
- Self-reported
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Health status
- Information collected
- Various for mother and father / for infant - atopic and respiratory diseases, infections, GI symptoms/disease, family history of diseases
- Questionnaire name/set of questions
- Set of questions
- Administration method
- Self-reported
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Biological samples and laboratory measurements
- Samples collected
- Stool
- Number of samples
- ~ 1,000 (ongoing)
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Microbiome
- Microbial material
- DNA, 16S rDNA (V3-V4)
- Number of samples/number of individuals
-
898
- Medium/tissue
- Feces
- Sampling collection method
- Frozen chain maintained during transport
- Time spent in room temperature
- None
- Sequencing platform
- Illumina MiSeq
- Read length/depth
- 250/>10,000
- Further details
- 16S rDMA amplicon sequencing
- Preservation method
- No (frozen at home and transported to Baby Well Clinics using cool transport containers)
- Information on type of meal last eaten prior to sample extraction available
- no