Food Chain Plus
Networks
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Datasets
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Variables
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Nutrition intervention studies, gut microbiome and host biomarkers for metabolic diseases
- Start Year
- 2014
- End Year
- 2020
- Funding
- BMBF
Visit FoCus
| Investigators | Contacts |
|---|---|
|
Design
- Study design
- Cross-sectional
- Follow Up
- baseline and 5-year recall completed, 5-year recalls are planned, data collection for the 10-year recall is currently ongoing
Marker Paper
Geisler C, Schlicht K, Knappe C, et al. Cohort profile: the Food Chain Plus (FoCus) cohort. Eur J Epidemiol. 2022;37(10):1087-1105. doi:10.1007/s10654-022-00924-y
PUBMED 36245062
Recruitment
- Sources of Recruitment
-
- Individuals
Number of participants
- Number of participants
- 1,811
- Number of participants with biosamples
- Supplementary Information
- 1133 M, 678 F
Timeline
focus
Selection Criteria
- Minimum age
-
18
- Maximum age
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83
- Newborns
- Twins
- Countries
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- Germany
- Territory
- International/National/Regional (region name)
- Europe
- Ethnic Origin
-
- Health Status
-
Recruitment
- Sources of recruitment
-
- General population
- Specific population
- Specific Population
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- Clinic patients
- Other specific population :
Number of participants
- Number of participants
- 1,811
- Number of participants with biosamples
Data Collection Event
- Start Date
-
2014
- End Date
-
2015
-
Measurements & methods
-
Dietary intake
- yes/no
-
- Information collected on habitual food intake collected
- Methods
-
- FFQ
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FFQ
- Questionnaire name/set of questions
- Postadam FFQ
- Type of questionnaire
- Semi-quantitative
- Administration method
- Self-reported
- Administration type
- Paper-based
- Reference period
- Year
- Portion size estimation
- Not quantified
-
Alcohol consumption
- Information collected
- Administration method
- Self-reported
- Administration type
- Paper-based
-
Tobacco consumption
- Information collected
- ever/never/current/packs per day
- Administration method
- Self-reported
- Administration type
- Paper-based
-
Anthropometric measurements
- Weight/height
- Self-reported, measured for subset
- Waist/hip circumference
- Self-reported, measured for subset
- Other measurements
- Various
-
Sociodemographic information
- Information collected
- Sex, age, residence, education, etc.
- Administration method
- Self-reported
-
Medication
- Information collected
- Drug dosage and drug name
- Antibiotics
- Last treatment and frequency collected
- Administration method
- Self-reported
-
Health status
- Information collected
- Various
- Questionnaire name/set of questions
- Various
- Administration method
- Self-reported
- Measurements
- Various
-
Biological samples and laboratory measurements
- Samples collected
- Blood, urine, stool
- Number of samples
- 1811
-
Biomarkers
-
Lipids
- Measurement(s)
- Various
- Medium
- Serum
-
Glucose
- Measurement(s)
- Various
- Medium
- Serum
-
Inflammation markers
- Measurement(s)
- Various
- Medium
- Serum
-
Adiposity biomarkers
- Measurement(s)
- Various
- Medium
- Serum
-
Other biomarkers
- Measurement(s)
- Various
- Medium
- Serum
-
Metabolomics
- Measurement(s)
- Direct infusion high resolution mass spectrometry
- Medium
- Serum, urine
- Untargeted approach
- yes
- Targeted groups
- Several
-
Genomics
- DNA available
- yes
- Number of samples/number of individuals
-
1,811
- Extraction protocol/ method
- Mircoarray
-
Microbiome
- Microbial material
- DNA, 16s rRNA V3 and V4 region
- Number of samples/number of individuals
-
1,545
- Library source and library selection
- Serum and urine metabolome
- Medium/tissue
- Faeces
- Sampling collection method
- Samples on dry ice
- Time spent in room temperature
- none
- Sequencing platform
- Illumina MiSeq
- Further details
- 16s
- Preservation method
- Cooled immediatley -80 within 24 hours
- Information on type of meal last eaten prior to sample extraction available
- no